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PARADIGM BIOPHARMACEUTICALS LIMITED.. - Announcements

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Paradigm Biopharmaceuticals Limited is a late-stage drug development company. The Company... Paradigm Biopharmaceuticals Limited is a late-stage drug development company. The Company is engaged in discovering, developing, and delivering pharmaceutical therapies. It is focused on the development of injectable pentosan polysulfate sodium (iPPS/PPS) for the treatment of osteoarthritis (OA) and mucopolysaccharidosis (MPS). Pentosan polysulfate sodium is a semi-synthetic drug manufactured from the wood chips of European beech trees. Extracted glucurono-xylans are sulfated to produce a negatively charged product that mimics glycosaminoglycans (GAGs). It develops PPS under the brand name Zilosul. PPS also inhibits the synthesis of the metalloproteinase, MMP-3 (Troeberg) involved in degrading cartilage. PPS also include treatment of joint function, mobility, and pain in patients with MPS; treating alphavirus-induced arthralgia (such as Ross River virus and Chikungunya); chronic heart failure (HF) and acute respiratory distress syndrome (ARDS).More

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PAR Response to ASX Price QueryPRICE SENSITIVE28/03/19
PAR Paradigm (PAR) Updated Investor PresentationPRICE SENSITIVE13/03/19
PAR Change of Director's Interest Notice08/03/19
PAR S&P DJI Announces March 2019 Quarterly RebalancePRICE SENSITIVE08/03/19
PAR Half Yearly Report and AccountsPRICE SENSITIVE21/02/19
PAR Cleansing Notice and Appendix 3B14/02/19
PAR PARADIGMS ORPHAN PHASE 2/3 CLINICAL PROGRAM PROGRESSESPRICE SENSITIVE14/02/19
PAR Appendix 4C - quarterlyPRICE SENSITIVE31/01/19
PAR PARADIGMS SUPPLEMENTARY PHASE 2B DATAPRICE SENSITIVE20/12/18
PAR PRESENTATION OF PHASE 2 CLINICAL TRIAL RESULTSPRICE SENSITIVE18/12/18
PAR PAR REPORTS SUCCESSFUL PHASE 2 CLINICAL TRIALPRICE SENSITIVE18/12/18
PAR PAR - Conference Call Details - Phase 2b OA Results17/12/18
PAR Trading HaltPRICE SENSITIVE14/12/18
PAR Change in substantial holding13/12/18
PAR Change of Director's Interest Notice13/12/18
PAR Appendix 3B and Cleansing Notice13/12/18
PAR PARADIGM REPORTS CONSISTENT OA PAIN REDUCTIONPRICE SENSITIVE07/12/18
PAR Cleansing Notice and Appendix 3B30/11/18
PAR Cleansing Notice and Appendix 3B27/11/18
PAR Results of Meeting26/11/18
PAR Paradigm's AGM PresentationPRICE SENSITIVE26/11/18
PAR Paradigm in-licenses treatment for rare joint diseasePRICE SENSITIVE22/11/18
PAR PARADIGM RECEIVES $2.32m R&D TAX INCENTIVE REFUNDPRICE SENSITIVE15/11/18
PAR PAR reports pain reduction in 145 people with osteoarthritisPRICE SENSITIVE07/11/18
PAR Cleansing Notice and Appendix 3B01/11/18
PAR Quarterly Report and Appendix 4C - quarterlyPRICE SENSITIVE31/10/18
PAR Notice of Annual General Meeting/Proxy Form26/10/18
PAR Paradigm Agreement With USA Past Players NetworkPRICE SENSITIVE25/10/18
PAR Paradigm's Updated Corporate PresentationPRICE SENSITIVE25/10/18
PAR Paradigm Raises A$9 MillionPRICE SENSITIVE25/10/18
PAR Trading HaltPRICE SENSITIVE23/10/18
PAR PAR REPORTS PAIN REDUCTION IN OA PATIENTSPRICE SENSITIVE25/09/18
PAR Phase2a RossRiver Virus Clinical Trial Recruitment FinalisedPRICE SENSITIVE28/08/18
PAR Appendix 4G and Corporate Governance Statement24/08/18
PAR Appendix 4E and 2018 Annual ReportPRICE SENSITIVE24/08/18
PAR PAR ACHIEVES 60 PER CENT REDUCTION IN OSTEOARTHRITIS PAINPRICE SENSITIVE15/08/18
PAR Cleansing Notice and Appendix 3B08/08/18
PAR PAR achieves 100 per cent recruitment in Phase 2b OA TrialPRICE SENSITIVE06/08/18
PAR Quarterly Report and Appendix 4C - quarterlyPRICE SENSITIVE27/07/18 download Created with Sketch. 508.08KB
PAR Cleansing Notice and Appendix 3B27/07/18 download Created with Sketch. 959.29KB
PAR Cleansing Notice and Appendix 3B17/07/18 download Created with Sketch. 835.26KB
PAR Response to ASX Price QueryPRICE SENSITIVE09/07/18 download Created with Sketch. 436.31KB
PAR Cleansing Notice and Appendix 3B04/07/18 download Created with Sketch. 1008.52KB
PAR Cleansing Notice and Appendix 3B26/06/18 download Created with Sketch. 836.38KB
PAR Appendix 3B and Cleansing Notice19/06/18 download Created with Sketch. 836.47KB
PAR PAR - 50% REDUCTION IN OSTEOARTHRITIS PAIN MAINTAINEDPRICE SENSITIVE15/06/18 download Created with Sketch. 127.93KB
PAR Cleansing Notice18/05/18
PAR Appendix 3B18/05/18
PAR Paradigm OA Phase 2b Clinical Trial over 80% RecruitedPRICE SENSITIVE17/05/18
PAR Change of Director's Interest Notice08/05/18
PAR Cleansing Notice08/05/18
PAR Appendix 3B07/05/18
PAR Appendix 4C - quarterlyPRICE SENSITIVE30/04/18
PAR PAR Non-Deal Roadshow Presentation17/04/18
PAR Corporate Governance Statement13/04/18
PAR PARADIGMs PHASE 2 CLINICAL DATA UPDATEPRICE SENSITIVE27/03/18
PAR PARADIGM REPORTS OSTEOARTHRITIS PAIN REDUCED BY 50%PRICE SENSITIVE01/03/18
PAR Half Year AccountsPRICE SENSITIVE22/02/18
PAR Quarterly Update and Appendix 4CPRICE SENSITIVE30/01/18
PAR Elite sportspeople successfully treated with PPS24/01/18
PAR PARs European Patent Granted for Bone Marrow Edema LesionsPRICE SENSITIVE16/01/18
PAR Paradigm Shareholder Newsletter20/12/17
PAR Paradigms Two Arthritis Phase 2 Clinical Trials on SchedulePRICE SENSITIVE23/11/17
PAR Appendix 3B and Cleansing Notice16/11/17
PAR Change in substantial holding15/11/17
PAR Change of Director's Interest Notice15/11/17
PAR Cleansing Notice - Section 708A15/11/17
PAR Paradigms ACL Phase 2 Clinical Trial SuccessPRICE SENSITIVE14/11/17
PAR Appendix 3B13/11/17
PAR Results of Meeting10/11/17
PAR CEO Update10/11/17
PAR PAR Successfully Completes A$5.75m PlacementPRICE SENSITIVE06/11/17
PAR Trading HaltPRICE SENSITIVE02/11/17
PAR PAR Updated Corporate Presentation02/11/17
PAR Appendix 4C - quarterlyPRICE SENSITIVE31/10/17
PAR First Participant Dosed in PARs Phase 2b OA Clinical TrialPRICE SENSITIVE30/10/17
PAR Response to ASX QueryPRICE SENSITIVE11/10/17
PAR Notice of Annual General Meeting/Proxy Form10/10/17
PAR PAR REPORTS PAIN REDUCTION IN 83% OF OSTEOARTHRITIS PATIENTSPRICE SENSITIVE10/10/17
PAR Appendix 3B28/09/17
PAR PARs Osteoarthritis Phase 2 Receives Ethics ApprovalPRICE SENSITIVE19/09/17
PAR Paradigm Phase 2 Ross River Virus Clinical Trial UpdatePRICE SENSITIVE14/09/17
PAR A PARADIGM SHIFT IN TREATING OSTEOARTHRITIS PAINPRICE SENSITIVE11/09/17
PAR Appendix 4G29/08/17
PAR Appendix 4E and 2017 Annual ReportPRICE SENSITIVE29/08/17
PAR Appendix 3B21/08/17
PAR Paradigm (PAR) - First Ross River Trial Participant TreatedPRICE SENSITIVE09/08/17
PAR Shares released from escrow03/08/17
PAR Appendix 4C - quarterlyPRICE SENSITIVE28/07/17
PAR Paradigm To Commence Phase 2 Ross River Virus Clinical TrialPRICE SENSITIVE10/07/17
PAR Appendix 3B04/07/17
PAR Change in substantial holding28/06/17
PAR Change of Director's Interest Notice26/06/17
PAR Paradigm Enters Heart Failure MarketPRICE SENSITIVE20/06/17
PAR Q and A on Hay Fever Program19/06/17
PAR Hay Fever Trial UpdatePRICE SENSITIVE16/06/17
PAR Trading HaltPRICE SENSITIVE15/06/17
PAR Paradigm Receives Ethics Approval for Ross River TrialPRICE SENSITIVE22/05/17
PAR Paradigms preclinical hay fever trial publishedPRICE SENSITIVE16/05/17
PAR Paradigm Non-Deal Roadshow Presentation15/05/17
PAR Response to ASX Price Query
28/03/19PRICE SENSITIVE
PAR Paradigm (PAR) Updated Investor Presentation
13/03/19PRICE SENSITIVE
PAR Change of Director's Interest Notice
08/03/19
PAR S&P DJI Announces March 2019 Quarterly Rebalance
08/03/19PRICE SENSITIVE
PAR Half Yearly Report and Accounts
21/02/19PRICE SENSITIVE
PAR Cleansing Notice and Appendix 3B
14/02/19
PAR PARADIGMS ORPHAN PHASE 2/3 CLINICAL PROGRAM PROGRESSES
14/02/19PRICE SENSITIVE
PAR Appendix 4C - quarterly
31/01/19PRICE SENSITIVE
PAR PARADIGMS SUPPLEMENTARY PHASE 2B DATA
20/12/18PRICE SENSITIVE
PAR PRESENTATION OF PHASE 2 CLINICAL TRIAL RESULTS
18/12/18PRICE SENSITIVE
PAR PAR REPORTS SUCCESSFUL PHASE 2 CLINICAL TRIAL
18/12/18PRICE SENSITIVE
PAR PAR - Conference Call Details - Phase 2b OA Results
17/12/18
PAR Trading Halt
14/12/18PRICE SENSITIVE
PAR Change in substantial holding
13/12/18
PAR Change of Director's Interest Notice
13/12/18
PAR Appendix 3B and Cleansing Notice
13/12/18
PAR PARADIGM REPORTS CONSISTENT OA PAIN REDUCTION
07/12/18PRICE SENSITIVE
PAR Cleansing Notice and Appendix 3B
30/11/18
PAR Cleansing Notice and Appendix 3B
27/11/18
PAR Results of Meeting
26/11/18
PAR Paradigm's AGM Presentation
26/11/18PRICE SENSITIVE
PAR Paradigm in-licenses treatment for rare joint disease
22/11/18PRICE SENSITIVE
PAR PARADIGM RECEIVES $2.32m R&D TAX INCENTIVE REFUND
15/11/18PRICE SENSITIVE
PAR PAR reports pain reduction in 145 people with osteoarthritis
07/11/18PRICE SENSITIVE
PAR Cleansing Notice and Appendix 3B
01/11/18
PAR Quarterly Report and Appendix 4C - quarterly
31/10/18PRICE SENSITIVE
PAR Notice of Annual General Meeting/Proxy Form
26/10/18
PAR Paradigm Agreement With USA Past Players Network
25/10/18PRICE SENSITIVE
PAR Paradigm's Updated Corporate Presentation
25/10/18PRICE SENSITIVE
PAR Paradigm Raises A$9 Million
25/10/18PRICE SENSITIVE
PAR Trading Halt
23/10/18PRICE SENSITIVE
PAR PAR REPORTS PAIN REDUCTION IN OA PATIENTS
25/09/18PRICE SENSITIVE
PAR Phase2a RossRiver Virus Clinical Trial Recruitment Finalised
28/08/18PRICE SENSITIVE
PAR Appendix 4G and Corporate Governance Statement
24/08/18
PAR Appendix 4E and 2018 Annual Report
24/08/18PRICE SENSITIVE
PAR PAR ACHIEVES 60 PER CENT REDUCTION IN OSTEOARTHRITIS PAIN
15/08/18PRICE SENSITIVE
PAR Cleansing Notice and Appendix 3B
08/08/18
PAR PAR achieves 100 per cent recruitment in Phase 2b OA Trial
06/08/18PRICE SENSITIVE
PAR Quarterly Report and Appendix 4C - quarterly
27/07/18PRICE SENSITIVE download Created with Sketch. 508.08KB
PAR Cleansing Notice and Appendix 3B
27/07/18 download Created with Sketch. 959.29KB
PAR Cleansing Notice and Appendix 3B
17/07/18 download Created with Sketch. 835.26KB
PAR Response to ASX Price Query
09/07/18PRICE SENSITIVE download Created with Sketch. 436.31KB
PAR Cleansing Notice and Appendix 3B
04/07/18 download Created with Sketch. 1008.52KB
PAR Cleansing Notice and Appendix 3B
26/06/18 download Created with Sketch. 836.38KB
PAR Appendix 3B and Cleansing Notice
19/06/18 download Created with Sketch. 836.47KB
PAR PAR - 50% REDUCTION IN OSTEOARTHRITIS PAIN MAINTAINED
15/06/18PRICE SENSITIVE download Created with Sketch. 127.93KB
PAR Cleansing Notice
18/05/18
PAR Appendix 3B
18/05/18
PAR Paradigm OA Phase 2b Clinical Trial over 80% Recruited
17/05/18PRICE SENSITIVE
PAR Change of Director's Interest Notice
08/05/18
PAR Cleansing Notice
08/05/18
PAR Appendix 3B
07/05/18
PAR Appendix 4C - quarterly
30/04/18PRICE SENSITIVE
PAR PAR Non-Deal Roadshow Presentation
17/04/18
PAR Corporate Governance Statement
13/04/18
PAR PARADIGMs PHASE 2 CLINICAL DATA UPDATE
27/03/18PRICE SENSITIVE
PAR PARADIGM REPORTS OSTEOARTHRITIS PAIN REDUCED BY 50%
01/03/18PRICE SENSITIVE
PAR Half Year Accounts
22/02/18PRICE SENSITIVE
PAR Quarterly Update and Appendix 4C
30/01/18PRICE SENSITIVE
PAR Elite sportspeople successfully treated with PPS
24/01/18
PAR PARs European Patent Granted for Bone Marrow Edema Lesions
16/01/18PRICE SENSITIVE
PAR Paradigm Shareholder Newsletter
20/12/17
PAR Paradigms Two Arthritis Phase 2 Clinical Trials on Schedule
23/11/17PRICE SENSITIVE
PAR Appendix 3B and Cleansing Notice
16/11/17
PAR Change in substantial holding
15/11/17
PAR Change of Director's Interest Notice
15/11/17
PAR Cleansing Notice - Section 708A
15/11/17
PAR Paradigms ACL Phase 2 Clinical Trial Success
14/11/17PRICE SENSITIVE
PAR Appendix 3B
13/11/17
PAR Results of Meeting
10/11/17
PAR CEO Update
10/11/17
PAR PAR Successfully Completes A$5.75m Placement
06/11/17PRICE SENSITIVE
PAR Trading Halt
02/11/17PRICE SENSITIVE
PAR PAR Updated Corporate Presentation
02/11/17
PAR Appendix 4C - quarterly
31/10/17PRICE SENSITIVE
PAR First Participant Dosed in PARs Phase 2b OA Clinical Trial
30/10/17PRICE SENSITIVE
PAR Response to ASX Query
11/10/17PRICE SENSITIVE
PAR Notice of Annual General Meeting/Proxy Form
10/10/17
PAR PAR REPORTS PAIN REDUCTION IN 83% OF OSTEOARTHRITIS PATIENTS
10/10/17PRICE SENSITIVE
PAR Appendix 3B
28/09/17
PAR PARs Osteoarthritis Phase 2 Receives Ethics Approval
19/09/17PRICE SENSITIVE
PAR Paradigm Phase 2 Ross River Virus Clinical Trial Update
14/09/17PRICE SENSITIVE
PAR A PARADIGM SHIFT IN TREATING OSTEOARTHRITIS PAIN
11/09/17PRICE SENSITIVE
PAR Appendix 4G
29/08/17
PAR Appendix 4E and 2017 Annual Report
29/08/17PRICE SENSITIVE
PAR Appendix 3B
21/08/17
PAR Paradigm (PAR) - First Ross River Trial Participant Treated
09/08/17PRICE SENSITIVE
PAR Shares released from escrow
03/08/17
PAR Appendix 4C - quarterly
28/07/17PRICE SENSITIVE
PAR Paradigm To Commence Phase 2 Ross River Virus Clinical Trial
10/07/17PRICE SENSITIVE
PAR Appendix 3B
04/07/17
PAR Change in substantial holding
28/06/17
PAR Change of Director's Interest Notice
26/06/17
PAR Paradigm Enters Heart Failure Market
20/06/17PRICE SENSITIVE
PAR Q and A on Hay Fever Program
19/06/17
PAR Hay Fever Trial Update
16/06/17PRICE SENSITIVE
PAR Trading Halt
15/06/17PRICE SENSITIVE
PAR Paradigm Receives Ethics Approval for Ross River Trial
22/05/17PRICE SENSITIVE
PAR Paradigms preclinical hay fever trial published
16/05/17PRICE SENSITIVE
PAR Paradigm Non-Deal Roadshow Presentation
15/05/17
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