Recent publication. Endomicroscopy sections based on a Five 1...

Recent publication. Endomicroscopy sections based on a Five 1 system. The new (approved by Zeiss) will offer many more enhancements than the Five 1.

http://journal.frontiersin.org/article/10.3389/fsurg.2016.00055/full

"We are standing on the threshold of the era of marker-assisted tumor management. Innovations in the fields of surgical optics, computer image analysis, and molecular bioengineering are advancing fluorescence-guided tumor resection paradigms, leading to cell-level approaches to visualization and resection of brain tumors."

"Nonetheless, confocal endomicroscopy with fluorescein in patients with brain tumors has revealed promising results on par with frozen section pathologic examination as a means of optically interrogating tissue (121)."

"Approval of targeted fluorescent probes for clinical use will likely stimulate the refinement of confocal endomicroscopy and its broad clinical use in neurosurgery and tumor pathology. These two technologies are complimentary and allow tailored, tumor-specific resections for personalized patient treatment and, certainly, precision tumor surgery. The ability to interrogate the tumor border optically is of significant advantage in the acquisition of selective biopsies of higher diagnostic yield. Such a situation could improve the neurosurgery–neuropathology workflow for increased efficiency."

"Therefore, the previously impossible may become routinely possible. If invading tumor cells are discovered in eloquent cortex, which is not normally resected, the neurosurgeon might be able to proceed on a cell-by-cell basis, targeting only tumor cells. Improved imaging technologies will bring about novel techniques to target or remove tissue or even individual cells. The advantages of such techniques are better surgical outcomes as nearly “cell-by-cell” or precision surgery becomes possible."

OIL prices at these levels won`t be around much longer!!