You can find trial details under ACTRN12611001076965 (since July 2016)
But to cut to the chase the POC assay was I-Stat TnI-Nx = Abbott on their I-Stat POC blood analyser..
I-Stat was put under the HC poster microscope back in 2015/26. From memory mjc159 (MUZ) established that the I-Stat did not have CLIA wavier - which may go on to explain why the Trial was held in NZ. I also don't think anyone could identify "Mix&Go" I-Stat involvement back then.
This is the best I can find on the new Tnl-Nx assay. ("paramagnetic" is all they give away.)
"eMethods. The manufacturer’s description if the i-STAT TnI-Nx point of care assay in the final stage of development.“The i-STAT TnI-Nx test is a new immunoassay test for cardiac troponin I. The i-STAT TnI-Nx test uses an enzyme-linked immunosorbent assay (ELISA) method leveraging paramagnetic beads and electrochemical detection of the resulting enzyme signal. The test reports a quantitative measurement of the sample concentration of cTnI in units of ng/L based on factory calibration. The ELISA is initiated when the test cartridge is inserted into the instrument. The instrument makes electrical, mechanical and thermal contact with the cartridge and controls the sample movement in the conduit. The sample dissolves the on-board reagents which are mixed into the test sample at a controlled temperature. During this phase, the cTnI in the sample is captured and labelled by the reagents. The sample is then positioned across an on-board magnetic which allows the paramagnetic beads to be drawn to the surface of the sensor. At the point the sensor is washed with the on-board wash fluid and the electrochemical detection occurs at the sensor surface. The current generated is measured by the instrument and is proportional to the concentration of cTnI in the sample.” Abbott, June 2018.
