POH 0.00% 0.0¢ progress 2023-2 trust

Complex, toxic or allergenic excipients • Unstable formulation...

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    Complex, toxic or allergenic excipients
    • Unstable formulation needing lyophilisation
    • Drugs too unstable to be an injectable
    • Need for ‘Cold chain’ to maintain stability
    • Reconstitution of lyophilised powders
    • Allergenic or toxic excipients
    • Post reconstitution stability, single use only
    • Incompatibility with injectable formulations


    TPM
    • A safer and more natural excipient
    • Improve stability reducing need to lyophilise
    • Allows previously unsuitable drugs to be injectable
    • Reduce ‘cold chain’ by improving RT* stability
    • Speed up reconstitution of lyophilised drugs
    • Replace problem excipients
    • Increase stability of reconstituted drugs –
    potentially allowing multi-use products
    • Enable injectable formulation
 
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