Well, a positive response to the o/n trials. BOS seems blessed...

Well, a positive response to the o/n trials. BOS seems blessed with many successes; usually biotechs have a much harder time of it. Still, the results were probably not all that BOS was hoping for…

What might be the significance of increasing the concentration of the active ingredient? It means a delay starting the Indian 6 month trial, pushing it into 2007. [That might have an impact on BOSOA Dec 06 options].

Maybe increased concentration means increased cost? Anyone have an idea how expensive this stuff is? I know Dr Reddy once upon a time couldn’t produce it in economic quantities, but how cheap it is to produce now is difficult to know.

Perhaps too, increased concentrations may harm the optical characteristics of the lenses.

On the other hand, maybe the concentrations used were conservative to lessen the likelihood of adverse results. It would be prudent to start with low concentrations and work your way up.

Hopefully this is just a matter of getting the balance right through trial and error.

Guess we’ll know in time…