In June 2017, a PCT patent application entitled Method of Treating Immunoglobulin Light Chain Amyloidosis was filed. This case covers the use of a known compound for the treatment of cardiac toxicity associated with light chain amyloidosis." PBT2?????
An announcement on pre-clinical the life-threatening AL amyloidosis would be nice. Amyloidosis can affect all organs, including the heart
Some amyloidosis info.
" Although there is no diagnosis code specific to AL amyloidosis and no validated method for identifying this condition using claims data, extrapolating from our data, there are at least 12 000 adults in the United States living with AL amyloidosis, and the number seems likely to rise."
http://www.bloodadvances.org/content/2/10/1046?sso-checked=true
"Prognosis in amyloidosis is dependent primarily on the degree of cardiac involvement and, in AL amyloidosis, on circulating light-chain levels. Because chemotherapy options have greatly expanded in recent years, prognosis for AL amyloidosis has markedly improved as well, with the life expectancy of most patients, including many of those with significant cardiac involvement, measured in years rather than months.
7,8 Prognosis in ATTR amyloidosis is generally better than in AL amyloidosis, though both forms of the disease still carry a high annual mortality."
http://www.acc.org/latest-in-cardiology/articles/2016/07/07/14/59/cardiac-amyloidosis