Guys, Overall Survival(OS) is the best gold standard end point...

Guys, Overall Survival(OS) is the best gold standard end point in cancer trails. Many times, even though the cancer drug works great and shows anti tumor with complete response, this doesn't mean the patient will have more survival rate/lives longer. On the other hand, patients who had disease stabilization, the survival rate is much longer than the patients who had seen complete response. Which drug would you prefer? is it the drug which provided longer survival life or short term better response and low survival ? In Oncology segment increasing the survival of patient is major accomplishment.

So prolonging the life of patient is much critical and important than just showing complete response or partial response with lower survival rate. There is much research to be done with vaccines still, so far I like the progress.