It's as good as a cure ..Readministration after long period of...

It's as good as a cure ..Readministration after long period of time?Safety, non drug comfort of life and cost effective.
This feb2018 company report
"to support entry of BB-301 into human clinical testing, we’re conducting our IND-enabling toxicology studies in sheep. The reason that we selected this species is that the weight of the animal and the size of key muscles in the upper digestive system are relatively consistent with human subjects. These features are key into using this model to support the route of administration of direct injection into cricopharyngeal muscle. This is the identical procedure used to administer botox as palliative care to OPMD patients, which only provides transient relief that is often ineffective. Utilizing gene therapy delivery vectors, we anticipate durability from the BB-301 treatment, which if consistent with other AAV vectors, may last years or perhaps even the lifetime of the patient following a single administration.With our current manufacturing procedures, the processes related to the production of BB-301 using baculovirus-based technologies to support the first in man studies later in Q4 2018 are currently being run at the 50-liter scale. Ultimately, manufacturing runs up to 250-liters will be used to produce large quantities of highly active BB-301 product for the clinical study in a cost-efficient manner."