Summary of the PCT patent WO2018218284 (A1) - NANOPARTICLE AGGREGATES", 6/12/18
The present disclosure relates to a method of inducing the controlled aggregation of nanoparticles comprising an amphiphilic coating, the method comprising contacting a plurality of said nanoparticles with an ionic solution comprising an organic solvent. Variation of one or more of the following experimental conditions can provide for further control of the aggregation process: molarity of the ionic solution, amount of organic solvent, temperature of the reaction, and surface charge of the nanoparticles. The nanoparticle aggregates are useful in a variety of applications including detection and quantitation assays. In one illustrative example, the nanoparticle aggregates are particularly useful in medical diagnostic applications.
Out of 25 CLAIMS of this patent (in patent, always Claim 1 is the mostimportant)
1. A method for inducing the controlled aggregation ofnanoparticles comprising an amphiphilic coating (Note: must be ionic), the method comprising contactinga plurality of said nanoparticles with an ionic solution comprising an organicsolvent.
Let's check Anteo:
The key is its unique metal-ion based naometre-thin chemistry (ionic solution to form thin film - coating, that glue nanoparticles through no-covalent bond), such as the proteins of interest for detection, BETTER than conventional methods (the advantage point of AnteoBind technology). I don't think Ellume's platform can survive ALONE WITHOUT Anteo. IMO
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