My timescale prediction for DARRT-1.
05 April 400mg group have all started treatment
19 April 400mg safety review (2 weeks)
800mg cohort cleared to start, allow two weeks to recruit
03 May 800mg group have all started treatment
17 May 400mg group first efficacy scan (6 weeks)
800mg safety review (2 weeks)
1200 mg cleared to start, allow two weeks to recruit
31 May 1200mg group have all started treatment
14 June 800mg first efficacy scan (6 weeks)
1200 mg safety review (2 weeks)
28 June 400mg second efficacy scan (12 weeks)
12 July 1200mg first efficacy scan (6 weeks)
Review first 3 cohorts, choose dose for cohort 4
26 July 800mg second efficacy scan (12 weeks)
09 August Cohort 4 fully recruited (allow 4 weeks)
23 August 1200mg second efficacy scan (12 weeks)
06 September
20 September Cohort 4 first efficacy scan
The first efficacy scans should be complete before the mid-year briefing takes place. It looks to be an exciting year!
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