This is what it says...
Clinical trial met the primary endpoint - change in the KOOS pain from baseline at Day 53 for the total trial population (p < 0.0001);
• Mean Change in KOOS Pain from Baseline – Total Population. Clinically meaningful and statistically significant results – see chart 1 below;
• Mean Change in KOOS Pain from Baseline – NRS:4-6 Strata. Clinically meaningful and statistically significant results – see chart 2 below;
• Mean Percentage Change in NRS Pain from Baseline – NRS:4-6 Strata. Clinically meaningful and statistically significant results (p<0.028) – see chart 3 below;
• Number of subjects with a >50% Reduction from Baseline in KOOS Pain Score at Day 53 – NRS:4-6 Strata. Clinically meaningful and statistically significant results (p<0.026) - see chart 4 below;
• Number of subjects with a >50% Reduction from Baseline in KOOS Pain Score at Days 11-81 – NRS:4-6 Strata. Clinically meaningful and statistically significant results (p<0.021) - see chart 5 below;
• Number of subjects with a >50% Reduction from Baseline in NRS Pain Score at Days 11-81 – NRS:4-6 Strata. Clinically meaningful and statistically significant results (p<0.02) - see chart 6 below;
• A key measure in pain outcomes is the Patient Global Impression of Change1 (PGIC) the total population and placebo was statistically (PGIC, p=0.0062);
• All secondary endpoints will be reported on Q1/Q2 CY2019;
• All data will be the subject of a peer-review publication in CY2019;
• Safety of drug confirmed; and
• Paradigm believes there is a high probability that the drug will be successful in a Phase 3 clinical trial and therefore will have big pharma licensing/partnering interest.
- Forums
- ASX - By Stock
- Ann: Paradigms Supplementary Phase 2B Data
This is what it says... Clinical trial met the primary endpoint...
-
-
- There are more pages in this discussion • 25 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add PAR (ASX) to my watchlist
(20min delay)
|
|||||
Last
57.5¢ |
Change
0.080(16.2%) |
Mkt cap ! $82.30M |
Open | High | Low | Value | Volume |
50.5¢ | 58.0¢ | 50.0¢ | $753.7K | 1.388M |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
2 | 3168 | 57.0¢ |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
57.5¢ | 102000 | 2 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
2 | 47906 | 0.245 |
3 | 82048 | 0.240 |
2 | 32293 | 0.235 |
8 | 110599 | 0.230 |
7 | 89672 | 0.225 |
Price($) | Vol. | No. |
---|---|---|
0.250 | 13363 | 1 |
0.255 | 34148 | 4 |
0.260 | 6415 | 2 |
0.270 | 19081 | 2 |
0.275 | 13636 | 2 |
Last trade - 12.31pm 04/12/2024 (20 minute delay) ? |
Featured News
PAR (ASX) Chart |