Skint, thanks, very interesting. This could cause difficulties...

Originallypostedbyskint

YouwouldthinkthatPranacouldhaveadvisedthemarket.InthepastwhentheyansweranASXquerythatalsowasmadepublic.Thematterof8-OHQasanantibioticisnotsonew.Thisisindependentresearchfrom2013:

[ResearchArticle:AntimicrobialActivityof8-HydroxyquinolineandTransitionMetalComplexesS.
Srisung,T.Suksrichavalit,S.Prachayasittikul,S.RuchirawatandV.Prachayasittikul
Abstract:Heterocycliccompoundslike8-hydroxyquinoline(8HQ)andderivativeshavebeenfoundinnaturalproductsandtherapeutics.
Herein8HQandmetalcomplexesof8HQ-5-substituted(X)uracils,X=I,NO2(1-6)wereinvestigatedfortheirantimicrobialpotency.Thecomplexes1-6exhibitedgrowthinhibitionagainstmanystrainsofgram-positiveandgram-negativebacteriawithminimuminhibitoryconcentrations(MICs)of575.71-718.76μM.Theinvestigatedcompound8HQwasshowntobeaverystrongantimicrobialagentwiththeMICof27.58μMthatcomparabletoampicillin(MIC26.93μM),thereferencedrug.Theactivityof8HQmostlywasobservedforresistantpathogens,gram-positivebacteriae.g.Staphylococcusaureus,Enterococcusfaecalisanddiploidfungus,Candidaalbicans.Thefindingsreveal8HQastheverypotentantimicrobialagentandaseriesof8HQtransitionmetalcomplexesasnovelantimicrobialsaswellastheapplicationsof8HQforthedesignandsynthesisofnewandpotentialtherapeuticleadcompounds.]
https://scialert.net/fulltextmobile/?doi=ijp.2013.170.175

Skint, thanks, very interesting. This could cause difficulties in getting a new patent, at least one obstacle. Smart co-operation between QU and Prana is needed, IMO. Lot of work to get a patent in general and in time. The time starts when there is the first public publication and I think there is only 6 months before the application needs to be filed, perhaps one year (???).