Interesting observation Congo...did anyone ask this at the AGM...

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30/07/18

12:11

Post #: 34622788
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Originally posted by hotcongo ↑

There does seem to be a bit of movement at the station, finally!

Here is something rather intriguing to try to make sense of:

FTT subjects are Margolis 1 types: either their ulcer has existed for longer than 6 months or it is larger than 5 square cms.

Let's assume half the subjects belong to the “had ulcer for longer than 6 months”.

All subjects are put onto FTT's version of standard care bandaging for two weeks and any subject whose ulcer shrank more than 30% in those two weeks got kicked out of contention because they responded too quickly to standard care.

So the subjects that made the cut were non-vigorous healers in response to being in the study and receiving the study's version of standard care.

Then, four weeks after treatment commenced, the total group of subjects , placebo and treatment groups, had shown a 50% reduction in ulcer size.

Why would someone, who belonged to the group that had had an ulcer for more than 6 months, and hadn’t shown rapid response during the two-week standard-care only phase, suddenly have their ulcer shrink 50% in four weeks?

Powerful placebo effect? A technique that errs on the side of generosity for measuring shrinking ulcers? A delayed kick-in effect from having compression bandaging applied conscientiously over 6weeks?

...Or perhaps a genuine treatment effect?

I wonder if any other VLU studies have shown a 50% ulcer size reduction 4 weeks after treatment in their combined treatment/placebo group, especially if they eliminating fast responders before starting the trial?

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Interesting observation Congo...did anyone ask this at the AGM presentation? If not, maybe an email to FTT would be useful?...or maybe we should start marketing the placebo....looks like it really works well.

FTT Price at posting: 5.6¢ Sentiment: Hold Disclosure: Held
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Interesting observation Congo...did anyone ask this at the AGM...

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