Memorable moments
- Noxopharm and Nyrada now have employees who have taken drugs through to commercialisation.
- Strategic and commercial master plans are being prepared, together with contingency plans, so that the company has ticked all boxes by the time Marketing Approval is granted
- Nyrada is focussed on non-oncology matters, but some discoveries such as the anti-inflammatory IRAK4 inhibitor announced in September also have anti-cancer potential.
- An independent expert will advise whether Nyrada should be re-merged into Noxopharm.
- Chief Medical Officer, Greg van Wyk, looks to be a great acquisition
- Multi-national Phase 2 Sarcoma trial to commence H1 2019. Rare cancer trials offer Fast Track Approval and Orphan Drug Status and approval based on smaller patient numbers
- DARRT registration trial for prostate cancer to commence H2 2019
- Professor Lenzo’s presentation can be found in lower half of https://www.noxopharm.com/site/PDF/1761_3/NOX2018AGMPresentations (about page 34).
- Radiotherapy looks to be the next big step in cancer treatment.
- Intravenous radiotherapy such as LuPSMA is effective for about 40% of patients, but has scope for improvement.
- Novartis has spent over $6 billion acquiring companies in this field.
- The decision to double numbers in the LuPIN trial at St Vincent’s (at considerable expense to Noxopharm) indicates that Veyonda significantly improves the performance of LuPSMA.
- More DARRT-1 results should be released in December. Patients have a life expectancy of about 6 months.
- Veyonda has the potential to be used as a radio-enhancer each time radiotherapy is used, including with early-stage cancer.
- Potential income is $42 billion per year at $10,000 per course. The Directors liked those numbers.
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