PBT 0.00% 0.0¢ prana biotechnology limited

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  1. 1,078 Posts.
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    YouwouldthinkthatPranacouldhaveadvisedthemarket.InthepastwhentheyansweranASXquerythatalsowasmadepublic.Thematterof8-OHQasanantibioticisnotsonew.Thisisindependentresearchfrom2013:

    [ResearchArticle:AntimicrobialActivityof8-HydroxyquinolineandTransitionMetalComplexesS.
    Srisung,T.Suksrichavalit,S.Prachayasittikul,S.RuchirawatandV.Prachayasittikul
    Abstract:Heterocycliccompoundslike8-hydroxyquinoline(8HQ)andderivativeshavebeenfoundinnaturalproductsandtherapeutics.
    Herein8HQandmetalcomplexesof8HQ-5-substituted(X)uracils,X=I,NO2(1-6)wereinvestigatedfortheirantimicrobialpotency.Thecomplexes1-6exhibitedgrowthinhibitionagainstmanystrainsofgram-positiveandgram-negativebacteriawithminimuminhibitoryconcentrations(MICs)of575.71-718.76μM.Theinvestigatedcompound8HQwasshowntobeaverystrongantimicrobialagentwiththeMICof27.58μMthatcomparabletoampicillin(MIC26.93μM),thereferencedrug.Theactivityof8HQmostlywasobservedforresistantpathogens,gram-positivebacteriae.g.Staphylococcusaureus,Enterococcusfaecalisanddiploidfungus,Candidaalbicans.Thefindingsreveal8HQastheverypotentantimicrobialagentandaseriesof8HQtransitionmetalcomplexesasnovelantimicrobialsaswellastheapplicationsof8HQforthedesignandsynthesisofnewandpotentialtherapeuticleadcompounds.]
    https://scialert.net/fulltextmobile/?doi=ijp.2013.170.175
    Skint, thanks, very interesting. This could cause difficulties in getting a new patent, at least one obstacle. Smart co-operation between QU and Prana is needed, IMO. Lot of work to get a patent in general and in time. The time starts when there is the first public publication and I think there is only 6 months before the application needs to be filed, perhaps one year (???).
 
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