Australia's largest stock trading and investment forum Australia's #1 stock forum

PBT

Click for more information

0.00%

0.0¢ prana biotechnology limited

CSF ferritin predicts brain hypometabolism, page-3

First 3 Last

Share
Profile

Follow
skint

3,630 Posts.

116

26/12/18

08:47

Post #: 36958023
Share

Originally posted by pivalde: ↑

I return to this paper because it is IMO a very important paper for PBT434 because it is a 5 y follow-up study in humans measuring mitochondrion function ( glucose consumption by repeated PET scans) and monitoring how brain iron load in human brains relates to this biomarker of mitochondrion function.

So this is a human study and it confirms that the more you have iron in your brain the higher is your risk to get AD. The evidence in this neurodegenerative process is very strong ( small study population but very significant finding in statistical analysis) . Iron is a very clear contributing factor in this neurodegenerative process.

Think about that in some 30% of normal humans this neurodegenerative process has started as early as when we are only 65y old.

We do not have a study how PBT434 will work in these cases, but if trading halt as anything to do with a possible partner, this paper is of big value. Just my opinion !

Expand

So pivalde, does this new info mean there is a way to check for PBT434 target engagement with iron in the brain? Or is it too late.

PBT Price at posting: 2.8¢ Sentiment: None Disclosure: Not Held
Upvote

0 Great analysis

Reply

Top Stories

MIN

MinRes's Ellison knows he screwed up – for that reason, hunt for new Chair to be sped up

AXP

Tambourah chases gold veins and mineralisation extension with drilling

WC8

Pan Asia rebranding to 'clear confusion' after bagging $35M for Chile projects

History-making uranium sample grades and an imminent drill run. Infini Resources is poised to transform in 2025

ACW

This biotech stock raised $11M in a risk-off environment. Its Alzheimer's drug could change the game

There are more pages in this discussion • 1 more message in this thread...

First 3 Last

Add PBT (ASX) to my watchlist

SPONSORED BY