Immutep Ltd.'s partner CYTLIMIC recently presented the results of its YNP001 study at the Society for Immunotherapy of Cancer (SITC) 2018 Annual Meeting.
The YNP001 study is a First-in-Human study of the cancer peptide vaccine CYT001, a combination immunotherapy with HSP70 derived peptide, GPC3 derived peptide, IMP321 and Hiltonol, for patients (total 17) with advanced or metastatic solid cancer.
The poster concludes:
The combination cancer vaccine therapy using multi-HLA-restricted peptides and hLAG-3Ig + Poly-ICLC was safe and effective for treating the last line patients with metastatic solid tumors. The proportion of the PD-1+/CD4+ T cells and Treg Fraction II were the significant biomarker for OS.
#SITC18
https://www.cytlimic.com/news/20181012_en.html
Ann: Positive interim TACTI-mel data presented at SITC, page-28
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