Lesion are used here as well as the primary indicator.....
"A more recent and larger retrospective analysis also demonstrated that the abscopal effect might not be as rare as initially believed, at least not when radiation is combined with ipilimumab [4]. In this study, 47 consecutive metastatic melanoma patients who were treated with ipilimumab and radiotherapy were analyzed. The radiation dose as well as the treated site varied, including both intra- and extra-cranial sites. The abscopal response was measured by assessing the response to an index lesion that is outside the radiation treatment field. The data were analyzed by courses of radiation as opposed to patients; there were 65 courses of radiation as some patients had more than one course. It was found that in 16 instances (25%), the index lesion decreased in size following radiation" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922506/
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