This is my first post on HC, like to add a few points.
I am an Anaesthetist. I have read all the trial research. I am very excited.
I first discovered PPS last year when my wife had Ross River Fever. I first tried her on the oral formulation, which did nothing, as it's bio-availability is around 5%. I managed to "access" injectable PPS. I spoke with the lead researcher for the initial PPS human trials at Griffith University. I spoke with the research team at Mater Hospital who were part of the Phase 2 trial. I didn't want my wife risking being placed in the placebo side of the double blind trial. I used the trial dosage regime. It was miraculous seeing my wife disabled with pain, some days using a walking stick, within weeks having no pain.
A month ago I injured my knee, had an MRI, lo and behold I had a full thickness cartilage tear, with bone marrow edema. I had constant pain, and could barely walk up or down stairs. Within a week of starting PPS I had probably a 90% pain reduction and could walk down stairs. This stuff works. And with no discernable side effects (for us).
I really don't know why PPS hasn't crossed over from Vet to Medical, but thankfully Paradigm are onto it. PPS, if it gets up, will cause a generational Medical change in how Osteo-Arthritis, and probably a whole raft of other Arthritides and injuries are treated. This is just the tip of the iceberg.
Opioids are awful. I prescribe a lot of them. There aren't really any other options for post-operative pain. Opioids shouldn't really have a place for treatment of chronic non-cancer pain. The occasional use for headache, injury is ok, but the evidence for use in arthritis really isn't there.....Opioid addiction is a big scourge, and a huge killer in our society now. There is a lot of interest in PPS, not just in treating pain, but actually reversing the course of a disease.
And yes, I have put my money where my mouth is from about 30c.....
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