Spinal fusion uses bone grafts to fuse 2 or more vertebrae together when the disc between them degenerates. It usually needs various supplements to get the grafts to fuse - and at one stage stem cells themselves were a candidate to enhance fusion.
What about the P3 ready MPC-25-Osteo, its' actual intention is to replace hip bone grafts for spinal fusion.
"A Phase 2 study has been completed where MPC-25-Osteo was implanted into the intervertebral disc space of 24 patients undergoing 1 or 2-level lumbar interbody fusion via posterior procedures. Click here for trial results."
http://www.mesoblast.com/product-candidates/spine-orthopedic-disorders/spinal-fusion
The stage the candidate from Ankasa Regenerative Therapeutics is at seems to be coming up for P2.
https://www.cirm.ca.gov/our-progress/awards/autologous-somatic-stem-cell-therapy-treatment-osteonecrosis
Cell Therapy News/Articles, page-360
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